Having to travel on a short week is tough for any team. Buy early on in the 2006 Thanksgiving Day game, the Buccaneers looked like worthy opponents for the Cowboys, driving for an early touchdown and a 7-0 lead.
But that would be the only advantage Tampa would have all day. Tony Romo made sure of that.
In his fifth start since taking over as the No. 1 quarterback, Romo put on a show in front of the national audience, tossing a career-best five touchdown passes.
Terry Glenn caught the first two, giving the Cowboys a first-quarter lead. Marion Barber caught two more and even Terrell Owens got in on the scoring fun, catching a seven-yard pass in the third quarter.
When it was all over, the Cowboys cruised to a 38-10 win over the Bucs, improving their all-time series record over Tampa Bay to 9-3, but it snapped a three-game losing streak to the Buccaneers.
Romo improved to 4-1 as a starter as the Cowboys, once 3-3, were now 8-5 and closing in on a playoff spot. The Cowboys eventually finished 10-6 and earned a Wild Card berth.